Introduction of PRF

Platelet Rich Fibrin: Introduction

by Dr Abhishek Mogre, Board Certified Oral & Maxillofacial Surgeon

Platelet Rich Fibrin commonly known as PRF is a second generation Platelet Growth Factor.
It is developed conveniently by using an appropriate Centrifuge to spin patients blood and divide it in 3 layers. The bottom layer after the spin, is composed primarily of Red Blood cells. The middle layer or PRF is composed of Platelets, Stem Cells and White Blood Cells held together in Fibrin network. The top layer is acellular plasma.

PRF is then separated and is prepared in variety of different ways as appropriate for the surgery.

PRF is different from the previous generation Platelet growth factors in the following ways:

1. It contains no additives such as Bovine Thrombin.
2. The PRF Gel which comprises of Fibrin, Platelets, White Blood Cells & Stem Cells is much more stable than all previous generation Platelet Growth Factors.
3. The Cytokines and Growth factors from PRF are released and available for 1-2 weeks compared to few hours or a day in previous generation Platelet Growth Factors.
4. The process of generating PRF is very simple, and requires a good peripheral IV access.

Shoreline Oral Facial Surgery & Dental Implants.